鼠抗CK16单克隆抗体(6F6) C1357
货号 | 中文名 | 规格 | 目录价(元) |
C1357-50 | 鼠抗CK16单克隆抗体(6F6) | 50μl | 880 |
C1357-100 | 鼠抗CK16单克隆抗体(6F6) | 100μl | 1500 |
CATALOG NUMBER: C1357
QUANTITY: 50μl 100μl
DESCRIPTION: Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.
SPECIFICITY: Human, Mouse, Rabbit
ISOTYPE: IgG1
MOLECULAR WEIGHT: ~51KD
APPLICATIONS: IHC: 1:100—1:500
*NOTE: Optimal working dilutions must be determined by the end user
STORAGE/HANDING: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Store at -20°C. Do not aliquot the antibody.
Immunochemistry
IHC staining of human gullet cancer tissue with CK16 mouse mAb(6F6) diluted at 1:200.
For research use only; not for use as a diagnostic.
Important Note: During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µL or less, we recommend gently dislodge any liquid in the container,‘s cap.
蛋白研究:蛋白提取、蛋白定量、Western Blot…核酸研究:核酸提取、PCR、核酸电泳… 抗体:单克隆抗体、多克隆抗体、酶标抗体… 细胞生物学:转染试剂、生化测定、细胞培养…
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