鼠抗NFkB p65单克隆抗体(14H2) C1354
货号 | 产品名称 | 规格 | 目录价(元) |
C1354-50 | 鼠抗NFkB p65单克隆抗体(14H2) | 50μl | 880 |
C1354-100 | 鼠抗NFkB p65单克隆抗体(14H2) | 100μl | 1500 |
QUANTITY: 50μl 100μl
DESCRIPTION: NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.
SPECIFICITY: Human, Mouse, Rabbit
ISOTYPE: IgG1
MOLECULAR WEIGHT: ~65KD
APPLICATIONS: WB: 1:1000-1:3000 IHC: 1:200
*NOTE: Optimal working dilutions must be determined by the end user
STORAGE/HANDING: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Store at -20°C. Do not aliquot the antibody.
Immunochemistry
IHC staining of mouse hippocampus tissue with NFκB p65 mouse mAb(14H2) diluted at 1:200.
For research use only; not for use as a diagnostic.
Important Note: During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µL or less, we recommend gently dislodge any liquid in the container,‘s cap.--> normal'>Important Note: During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µL or less, we recommend gently dislodge any liquid in the container,‘s cap.
蛋白研究:蛋白提取、蛋白定量、Western Blot…核酸研究:核酸提取、PCR、核酸电泳… 抗体:单克隆抗体、多克隆抗体、酶标抗体… 细胞生物学:转染试剂、生化测定、细胞培养…
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